North Jersey Section of the ACS

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Welcome to the North Jersey ACS Drug Metabolism Discussion Group

Our mission: We are dedicated to fostering a continued discussion on the scientific advances in drug metabolism among the industrial and academic community. We sponsor multiple meetings each year at which world renowned scientists give presentations. The format of these meetings range from dinner presentations and mini-symposiums to our annual 1-2 day fall symposium.

[ Upcoming or Most Recent Meeting | Past Meetings | Steering Committee ]

Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]


2012 Fall Symposium and Vendor Exhibition

2012 Fall Symposium and Vendor Exposition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Toward a Better Understanding of Drug Metabolism and Transport: Novel Model Systems, Environmental Influence, and Liability Prediction”

at the

Hotel Somerset Bridgewater
(formerly Crowne Plaza, formerly Somerset Plaza)

110 Davidson Avenue
Somerset, NJ 08873

[ directions ]

October 11, 2012
8:00 am – 3:45 pm

Toward a Better Understanding of Drug Metabolism and Transport: Novel Model Systems, Environmental Influence, and Liability Prediction

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Dr. Allen Jones, Chair, NJDMDG

9:10 a.m.

Investigating Chemotherapeutic Drug Disposition and Toxicity using Transporter Knockout and Humanized Mice

Dr. Lauren Aleksunes, Assistant Professor, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ

10:00 a.m.

Evolving Trends in Complex Culture Systems and Their Utility in Drug Development: Focus on hepatotoxicity

Mr. Albert Reising , Lab Head- Models of Organ Toxicity, Novartis Pharmaceuticals, East Hanover, NJ

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Identifying and Eliminating Biotransformation Liabilities Early in Drug Discovery

Dr. Kaushik Mitra, Department of Pharmacodynamics, Pharmacokinetics and Drug Metabolism, Merck, Rahway, NJ

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Induction of Mouse Carboxylesterase Expression and Function following Developmental Pesticide Exposure: Role of the Constitutive Androstane Receptor the role of environment and development in regulating metabolism

Dr. Jason Richardson, Assistant Professor, Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, and Resident Member Environmental and Occupational Health Sciences Institute, Piscataway, NJ

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

UGT phenotyping, clearance predictions and DDI assessment

Dr. Theunis Goosen, Associate Research Fellow,  Pfizer

3:45 p.m.

Program Closure

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NJDMDG Steering Committee 2012-2013:

Name Company E-mail address Responsibility
Allen Jones Roche Chair 2012-13
Philip Krieter Warner Chilcott Treasurer
Karl Frank Roche Vice-Treasurer
Donglu Zhang BMS Vendor Liaison
Karen H. Dingley Merck Research Vendor Liaison
Lian Zhou BMS Past Chair, 2011-12
Imad Hanna Novartis Past Chair, 2010-11
Shiying Chen Merck Research Member
Lauren Aleksunes Rutgers University Member
Maria Markowska Janssen R & D Member
Wing Lam Janssen R & D Member
Zhao pie Zeng Sanofi-aventis Member
Lei Tang Sanofi-aventis Member
Richard Tschirret-Guth Merck Research Member
Bo Wen Roche Member
Manthena Varma Pfizer Member
Sekar Surapaneni Celgene Member

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Registration:

  • Pre-registration fee is $125 (up to one week before the meeting).
  • Registration is Free for students and unemployed (with proper identification).
  • Registration fee at the door is $150 (Checks only).
  • Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee from your organization (see Committee).
  • If you have no DMDG member at your company, please contact Allen Jones () for registration.

  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.

Exhibitors:

  • Please contact Karen Dingley () for information concerning exhibits

Directions to the:

Hotel Somerset Bridgewater
        (formerly Crowne Plaza)
        (formerly Somerset Plaza)

110 Davidson Avenue, Somerset, NJ 08873

Phone: 732-560-0500

 

    From the New Jersey Turnpike:

    Exit 10 to Interstate 287 North.  Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook).  Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)

    From New York City:

    Lincoln Tunnel to N.J. Turnpike South.  Follow N.J. Turnpike directions mentioned above.

    From Route 287:

    If traveling north:

    Exit 10 (527 New Brunswick-South Bound Brook).  Follow sign towards Bound Brook, to light make left (Davidson Ave.)

    If traveling south:

    Exit 10 (527 New Brunswick).  Left on Easton Ave., to light, make left (Davidson Ave).

     

    From the Newark Airport

    Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.

Top



Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]


2012 Fall Symposium and Vendor Exhibition

Top

2012 Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Current Topics in DMPK
and the New DDI Draft Guidance”

Crowne Plaza Somerset-Bridgewater Hotel
110 Davidson Avenue
Somerset, New Jersey
April 26, 2012
8:00 am – 3:45 pm

[ registration | directions ]

2012-04-26-DMDG-symposium

Program

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Dr. Lian Zhou, Chair, NJDMDG

9:10 a.m.

[ slidesPDF ]

Drug Metabolism in Chimeric Mice with Humanized Liver

Professor Hiroshi Yamazaki, Showa Pharmaceutical University, Machida, Tokyo.

10:00 a.m.

[ slidesPDF ]

ADME in NAFLD: Genes and Big Jeans Increase the Risk of Adverse Drug Reactions

Professor Nathan Cherrington, Pharmacology & Toxicology, University of Arizona, Tucson, AZ.

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

[ slidesPDF ]

Clarity on Transporters: Navigating the New FDA Draft Guidance on Drug Interactions

Dr. Sid Bhoopathy, Chief Operating Officer, Absorption Systems, Exton, PA.

 12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

[ slidesPDF ]

The 2012 FDA Draft Guidance on Drug-drug Interactions: Enzyme Induction and Beyond

Dr. Michael Sinz, Research Fellow, Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Wallingford, CT.

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

Update on the Progress of the IQc/FDA/Academia Collaboration on DDI Prediction and Thoughts on the DDI Draft Guidance

Dr. Scott Obach, Senior Research Fellow, Pharmacokinetics, Dynamics, and Drug Metabolism Department, Pfizer, Groton, CT.

3:45 p.m.

Program Closure

Top

Registration:

     Pre-registration fee is $125 (by April 13, 2012).

     Registration fee is waived for students, postdocs, faculty, retirees and unemployed ACS members (with proper identification).

     Registration fee at the door is $150 (Checks only).

     Please plan to pre-register as a group, as coordinated by a member of the NJDMDG steering committee from your organization (see list at end).

     If you have no NJDMDG member at your company, please contact Lian Zhou () for registration.

     Payments by personal or company checks.  Sorry, credit cards are not accepted. 

     Checks should be made payable to: NJ Drug Metabolism Discussion Group.  

 

Exhibitors:

     Please contact Donglu Zhang () for information concerning exhibits


Directions to the:

Crowne Plaza Somerset-Bridgewater Hotel   (Formerly Somerset Plaza Hotel)

110 Davidson Avenue, Somerset, NJ  08873

Phone: 732-560-0500

 

From the New Jersey Turnpike:

Exit 10 to Interstate 287 North.  Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook).  Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)

From New York City:

Lincoln Tunnel to N.J. Turnpike South.  Follow N.J. Turnpike directions mentioned above.

From Route 287:

If traveling north:

Exit 10 (527 New Brunswick-South Bound Brook).  Follow sign towards Bound Brook, to light make left (Davidson Ave.)

If traveling south:

Exit 10 (527 New Brunswick).  Left on Easton Ave., to light, make left (Davidson Ave).

 

From the Newark Airport

Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.

 


Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]


2011 Fall Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

Emerging Areas in DMPK:
From CYPs and Transporters to Drug Interactions”

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey
October 6, 2011
8:00 am – 3:45 pm

[ registration ]

Program

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Dr. Lian Zhou, Chair, NJDMDG

9:10 a.m.

New Insights on the Interplay of Intestinal CYP3A and P-gp in Influencing Intestinal Absorption of Dual Substrates

Dr. Dhiren Thakker, Ferguson Distinguished Professor and Associate Dean,
Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, University of North Carolina, Chapel Hill, NC

10:00 a.m.

[ slidesPDF ]

Active Intestinal Drug Uptake: The Double-Edged Sword Transporters

Dr. Imad Hanna, Senior Fellow, Drug Metabolism and Pharmacokinetics, Novartis, East Hanover, NJ

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

[ slidesPDF ]

Pro-drug strategies to leverage transporters

Dr. James Polli, Professor of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

ADME of Biologics – What Have We Learned from Small Molecules?

Dr. Thomayant Prueksaritanont, Sr. Scientific Director, Preclinical Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck, West Point, PA Malvern, PA

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

[ slidesPDF ]

Assessing modeling and simulation tools and methods for predicting drug interactions caused by induction (FDA/Industry/Academia Induction Group Work Product)

Dr. Scott Obach, Senior Research Fellow, Pfizer Groton, CT

3:45 p.m.

Program Closure



Registration:

Pre-registration fee is $125 (by September 30, 2011).

Registration is Free for students and university faculties (with proper identification).

Registration fee at the door is $150 (Checks only).

 

       Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see Steering Committee list below).

       If you have no DMDG member at your company, please contact Lian Zhou () for registration.

       Payments by personal or company checks.  Sorry, credit cards are not accepted. 

       Checks should be made payable to: NJ Drug Metabolism Discussion Group. 

       Please also visit our website: https://legacy.njacs.org/drugmet.html

 

Exhibitors:

       Please contact Karen Dingley () for information concerning exhibits

 

Directions to the Somerset Crowne Plaza Hotel:

    110 Davidson Avenue, Somerset, NJ
    Phone: 732-560-0500

    From the New Jersey Turnpike:

      Exit 10 to Interstate 287 North.  Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook).  Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)

    From New York City:

      Lincoln Tunnel to N.J. Turnpike South.  Follow N.J. Turnpike directions mentioned above.

    From Route 287: If traveling north:

      Exit 10 (527 New Brunswick-South Bound Brook).  Follow sign towards Bound Brook, to light make left (Davidson Ave.)

    From Route 287: If traveling south:


      Exit 10 (527 New Brunswick).  Left on Easton Ave., to light, make left (Davidson Ave).

    From the Newark Airport


      Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.



Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]


2011 Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

Current Scientific Concepts and Practices in DMPK: Drug Transporters, DDI, Formulation Strategies, and Clinical Pharmacology

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey
April 13, 2011
8:00 am – 3:45 pm

Program

Current Scientific Concepts and Practices in DMPK: Drug Transporters, DDI, Formulation Strategies, and Clinical Pharmacology

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

[ slidesPdf ]

Introductory Remarks

Dr. Imad Hanna, Chair, NJDMDG

9:10 a.m.

[ slidesPDF file ]

Structure and Function of Human “Multidrug And Toxin Extruders” (MATEs)
Dr. Stephen Wright, Professor of Physiology, Biochemistry and Molecular Biophysics, Department of Physiology, University of Arizona, Tucson, AZ.

10:00 a.m.

[ slidesPDF file ]

Factors Influencing Drug Delivery to the Brain:  Multiple Mechanisms at Multiple Barriers

Dr. William F. Elmquist, Professor and Department Head

Department of Pharmaceutics, University of Minnesota, Minneapolis MN.

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

[ slidesPDF file ]

Irreversible Inhibition of CYP2C19 by Some but not all Proton Pump Inhibitors and its Relevance to the Anti-Platelet Effect of Clopidogrel (Plavix)

Dr. Andrew Parkinson, Chief Scientific Officer, XenoTech LLC, Lenexa, KS.

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Formulation-Dependent PK/PD and Human Dose Projections Using In silico, In vitro and In vivo Data

Dr. Tycho Heimbach, Senior Investigator, Drug Metabolism and Pharmacokinetics, Novartis Institute for BioMedical Research, East Hanover, NJ.  

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

[ slidesPDF file ]

Developing the Clinical Pharmacology Section of a U.S. Package Insert

Dr. Philip Mayer, Assistant Vice President of Clinical Pharmacology, Pfizer Global Research and Development, Collegeville, PA.

3:45 p.m.

Program Closure




Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]


2010 Fall Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Drug Metabolism/Transport Interplay: Regulatory, Therapeutic and Toxicological Implications”

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey

October 13, 2010
8:00 am – 3:45 pm

Program

Drug Metabolism/Transport Interplay: Regulatory, Therapeutic and Toxicological Implications

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

[ slidesPdf ]

Introductory Remarks

Dr. Imad Hanna, Chair, NJDMDG

9:10 a.m.

[ slidesPdf ]

Regulation of Renal Drug Transport under Physiological and Pathological Conditions

Dr. Rosalinde Masereeuw, Associate Professor, Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, The Netherlands

10:00 a.m.

[ slidesPdf ]

Pharmacokinetic Determinants of Statin-Induced Myopathy

Dr. Rommel G. Tirona, Assistant Professor, Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 a.m.

[ slidesPdf ]

Membrane Transporters in Drug Development

Dr. Raymond Evers, Director, Transporters and In Vitro Technologies, Drug Metabolism and Pharmacokinetics, Merck and Co. Rahway, NJ.

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Presentation to be posted at a later date

Regulatory Interplay between Vitamin D and CYP3A4 in the Small Intestine

Dr. Kenneth E. Thummel, Professor and Chair, Department of Pharmaceutics, University of Washington, Seattle, WA.

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

[ slidesPdf ]

Inter-Individual Variability in Human Drug Glucuronidation: What We Know and What We Need to Know

Dr. Michael H. Court, Associate Professor, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA.

3:45 p.m.

Program Closure

 

Registration:

Pre-registration fee is $125 (by Oct 7, 2009).

Registration is Free for students (with proper identification).

Registration fee at the door is $150 (Checks only).

 

       Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list at end).

       If you have no DMDG member at your company, please contact Imad Hanna () for registration.

       Payments by personal or company checks.  Sorry, credit cards are not accepted. 

       Checks should be made payable to: NJ Drug Metabolism Discussion Group. 

       Please also visit our website: https://www.njacs.org/drugmet.html

 

Exhibitors:

       Please contact Karen Dingley () for information concerning exhibits

 



Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]


2010 Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Transporters, Discovery Metabolism, and Heavy Drugs”

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey


April 22, 2010
8:00 am – 3:30 pm

Program

Transporters, Discovery Metabolism, and Heavy Drugs

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Dr. Philip Krieter, Chair, NJDMDG

9:10 a.m.

[ slidesPdf ]

Monocarboxylate Transporters in Drug Disposition: Role in the Toxicokinetics and Toxicodynamics of the Drug of Abuse GHB  

Dr. Marilyn E. Morris, Professor, Department of Pharmaceutical Sciences, University at Buffalo, State University of New York

10:00 a.m.

[ slidesPdf ]

Disposition and Elimination of Organic Anions and Cations: Transporters and Decision Trees  

Dr. Douglas H. Sweet, Associate Professor, Department of Pharmaceutics, Virginia Commonwealth University

10:45 a.m.

Vendor Exhibit & Coffee Break

11:15 a.m.

[ slidesPdf ]

Transporter Polymorphisms  

Dr. Kathleen Hillgren, Research Advisor, Lilly Research

12:00 Noon

Lunch & Vendor Exhibit

1:30 p.m.

[ slidesPdf ]

What is Down the Road for Drug Metabolism Support of Drug Metabolism?  

Dr. Ronald E. White, Distinguished Research Fellow, Pharmaceutical Candidate Optimization, Bristol-Myers Squibb

2:15 p.m.

Vendor Exhibit & Coffee Break

2:45 p.m.

[ slidesPdf ]

Deuterated Drugs: Opportunities and Limitations  

Dr. Aarti Sawant, Senior Scientist, PDM-CNS Discovery, Pfizer, Inc.

3:30 p.m.

Program Closure

Registration:

Pre-registration fee is $125 (by April 14, 2010).

Registration is free for students (with proper identification).

Registration fee at the door is $150 (checks only).

       Please plan to pre-register as a group, coordinated by a member of the NJACS DMDG steering committee from your organization (see list below).

       If you have no DMDG member at your company, please contact Phil Krieter () for registration.

       Payments by personal or company checks.  Sorry, credit cards are not accepted. 

       Checks should be made payable to: NJ Drug Metabolism Discussion Group. 

 

Exhibitors:

Please contact Karen Dingley () for information concerning exhibits.



Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]


October 14, 2009 – Fall Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Transporters, Current Industry Practices, and Biologics”

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey

October 14, 2009
8:00 am – 3:30 pm

Program

Transporters, Current Industry Practices, and Biologics

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

8:50 a.m.

Introductory Remarks

Dr. Philip Krieter, Chair, NJ-DMDG

9:00 a.m.

[ slidesPdf ]

The Challenges of Designing Cyclic Prodrugs of Opioid Peptides that Permeate the Intestinal Mucosa and the Blood-Brain Barrier

Dr. Ron Borchardt, Solon E. Summerfield Distinguished Professor, Department of Pharmaceutical Chemistry, School of Pharmacy,  University of Kansas

9:50 a.m.

[ slidesPdf ]

In Vitro and In Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of American Perspective

Dr. Gondi Kumar, Senior Director, Department of Drug Metabolism and Pharmacokinetics, Celgene Corporation

10:45 a.m.

Vendor Exhibit & Coffee Break

11:15 a.m.

[ slidesPdf ]

Inactivation Studies for Predicting Drug-Drug Interactions. Pharmaceutical Industry Recommendations and Recent Observations

Dr. R. Scott Obach, Senior Research Fellow, Biotransformation Group, Pharmacokinetics, Dynamics and Drug Metabolism Department, Pfizer, Inc.

12:00 Noon

Lunch & Vendor Exhibit

1:30 p.m.

[ slidesPdf ]

Pharmacokinetic Based Drug-Drug Interactions of Biologicals. Science and Development Strategies

Dr. Frank-Peter Theil, Associate Director, Genentech, Inc.

2:15 p.m.

Vendor Exhibit & Coffee Break

2:45 p.m.

[ slidesPdf ]

PK/PD Study Strategies for Biopharmaceuticals: Is Bigger Better?

Dr. Sharon A. Baughman, Biotechnology Consulting

3:30 p.m.

Program Closure

 

 

Registration:

Pre-registration fee is $125 (by Oct 7, 2009).

Registration is free for students (with proper identification).

Registration fee at the door is $150 (Checks only).

        Please plan to pre-register as a group, coordinated by a member of the NJACS DMDG steering committee from your organization (see list below).

        If you have no DMDG member at your company, please contact Phil Krieter () for registration.

        Payments by personal or company checks.  Sorry, credit cards are not accepted. 

        Checks should be made payable to: NJ Drug Metabolism Discussion Group. 

 

Exhibitors:

Please contact Karen Dingley () for information concerning exhibits

 

 


Fall 2012  |  Spring 2012  |  Fall 2011  |  Spring 2011  |  Fall 2010  |  Spring 2010  |  Fall 2009  |  Spring 2009  ]



April 29, 2009 – Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Current Topics in Drug Metabolism and Pharmacokinetics: Biologics and Transporters – What's New?”

Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey

April 29, 2009
8:45 am – 3:30 pm

PROGRAM
Current Topics in Drug Metabolism and Pharmacokinetics

Biologics and Transporters – What's New?

TIME

 

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

 

 

8:50 a.m.

Introductory Remarks

 

Dr. Robert M. Iannucci, Chair, NJDMDG

 

Johnson & Johnson, Raritan, NJ

 

 

9:00 a.m.

Imaging Techniques and Pharmacokinetic Modeling/Simulation: Useful Quantitative Tools for the Drug Transport Scientist

 

[ slidesPdf ]

Dr. Kim Brouwer, Professor and Chair of the Division of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, and Professor, Curriculum in Toxicology, University of North Carolina

 

 

9:50 a.m.

Regulation of Organic Anion Transporters and the Clinical Implication

 

[ slidesPdf ]

Dr. Guofeng You, Professor in the Department of Pharmaceutics, the Ernest Mario School of Pharmacy, Rutgers University

 

 

10:45 a.m.

Vendor Exhibit and Coffee Break

 

 

11:15 a.m.

Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling of Biologics

Dr. Donald E. Mager, Professor, Pharmaceutical Sciences, University at Buffalo, State University of New York

 

 

12:00 Noon

Lunch and Vendor Exhibit

 

 

1:30 p.m.

Role of Transporters in Drug Exposure During Lactation

 

[ slidesPdf ]

Dr. Patrick McNamara, Professor and Chair of the Department of Pharmaceutical Sciences, School of Pharmacy, University of  Kentucky

 

 

2:15 p.m.

Vendor Exhibit and Coffee Break

 

 

2:45 p.m.

Regulatory and Scientific Issues that Impact Development of Biotherapeutics

 

[ slidesPdf ]

Dr. Peter Thomas, Senior Program Manager, Early Development, Covance Laboratories, Inc, Madison, WI

 

 

3:30 p.m.

Program Conclusion

Top

In addition to our annual Fall Symposium, we try to sponsor 1-2 smaller meetings or mini-symposia in the Spring and Summer.


Please use our

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